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Patients should be encouraged to engage in regular moderate-intensity exercise, starting with short durations (10-15 minutes) if necessary and gradually increasing
Each step is roughly a doubling, giving five escalation periods
SPL UNCLASSIFIED SECTION Patients with Renal Impairment Renal impairment does not impact the pharmacokinetics of tirzepatide
Because GIP receptor activation affects fat metabolism through pathways separate from appetite control, there is a theoretical basis for better weight maintenance at lower tirzepatide doses compared to equivalent semaglutide doses
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