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571 For example, defective N1-methyladenosine (m 1 A) modification in mt-tRNA Lys and mtDNA mutation-caused tRNA Ala reduction, discovered through tRNA sequencing, have provided valuable insights into the pathogenesis of mitochondrial diseases

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Intrathecal administration of GLP-1R agonists such as GLP-1(736) and exenatide alleviated hypersensitivity in models of formalin-induced, peripheral nerve injury-induced, bone cancer-induced, and diabetes-induced pain in mice and rats [31]