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Second, the limited data suggest unique safety and monitoring aspects

Sharon Barr, executive vice president, biopharmaceuticals R&D at AstraZeneca, said, Building on the promising Phase I clinical data generated by Eccogene, we believe this oral GLP-1RA molecule could offer alternatives to current injectable therapies both as a potential monotherapy as well as in combination for cardiometabolic diseases such as type 2 diabetes, as well as for obesity

Unlike cagrilintide, tirzepatide has completed a large Phase 3 program and reached the market

A Historic Approval Pathway The FDA cleared orforglipron just 50 days after its application was filed, some 294 days ahead of the originally assigned PDUFA date of 20 January 2027