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Pre-clinical studies involving crizotinib (IC50 4.14.7uM) showed to be effective against HNSCC cell lines as well as had a significant inhibition of both wound-closure and invasion [111]
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Following treatment, characteristic differences were detected through either a within-subjects comparison (i.e., the before/after difference) or a between-subjects comparison (i.e., the treatment/no-treatment difference)
The clinical layer dominates by citation count and is the least useful for laboratory design
