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(133) reported six binding/unbinding pathways (PW1, PW2, PW3, PW4, PW1a, and PW4a) of phenol to/from the R 6 insulin hexamer and its mutants (IleA10 to Val and GluB13 to Gln)
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In published research it has been investigated for its effects on tissue repair, angiogenesis, gastrointestinal mucosal protection and anti-inflammatory signalling in animal and cell-culture models
This distinction helps explain why it progressed into formal obesity trials, whereas the raw fragment itself did not
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