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There is emerging evidence for benefits of metabolic surgery and three classes of glucose-lowering therapy (GLP-1 RA, SGLT2i, and GIP and GLP-1 RA) [188, 292,293,294,295,296,297,298, 316]
Tirzepatide is a once-weekly injectable medication approved by the FDA for the treatment of type 2 diabetes mellitus (marketed as Mounjaro) and chronic weight management in adults with obesity or overweight with weight-related comorbidities (marketed as Zepbound)
Most are administered via subcutaneous injection, though oral formulations like semaglutide are now available
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