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[2] If you experience concerning symptoms after an injection, seek medical advice and consider reporting suspected side effects through the MHRA Yellow Card scheme

Suspected adverse reactions should be reported to the MHRA via the Yellow Card Scheme (yellowcard.mhra.gov.uk)

The post-opening discard period exists because: Sterility can no longer be fully guaranteed after first puncture Preservatives slow microbial growth but do not eliminate contamination risk Risk of contamination increases with repeated vial access For this reason, healthcare and laboratory settings typically follow a fixed discard timeframe (commonly 28 days), unless otherwise specified by the manufacturer

PMC / Aging Cell (2025) PMC12727671 Confirmed age-related NAD+ decline across multiple species (rodents, nematodes, and select human tissues including skin, liver, and brain)