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The latest data for orforglipron, a daily oral small molecule GLP-1 mimic developed by Lilly for weight management and T2D, showed around 10.5% weight loss in the ATTAIN-2 clinical trial in diabetic patients, compared to 2.2% weight loss for those on placebo
The medication should only be prescribed for its FDA-approved indications of type 2 diabetes or weight management, with any potential cognitive benefits considered theoretical and unproven
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