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However, veterinarians might recommend liver supplements for: Dogs with medical conditions like liver cancer, liver infection, and liver failure Dogs with digestion issues (the liver plays a key role in digestion) Dogs who eat a homemade diet, because they may lack or be deficient in nutrients necessary for proper liver functioning Senior dogs and dogs on medication A liver supplement is typically given for long-term liver support, but your veterinarian can determine how long your dog would need to take the supplement

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And though they typically last between several days and several weeks, they may persist for as long as you take the medication