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2019;12:CD013505
Their standard titration protocol starts at 3mg daily for the first four weeks, then increases to 4mg daily for maintenance
In summary, alterations at the glutathione activator site result in an absent geometric and electrostatic complementary 3,50 for the reducing agent, explaining the inefficient reduction of numerous glutaredoxins 12,25,26,27,28,29,48 and thioredoxins by GSH
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