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Published clinic protocols generally describe 100-300 mcg of each peptide per injection, administered subcutaneously before sleep, on a 5-days-on / 2-days-off schedule, with cycles typically running 1-3 months on followed by a rest period

A variety of approaches aimed at targeting IGF-1R has been utilised to prove the concept, or are being developed for potential anticancer therapies

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With prolonged use, the pituitary's natural GH output decreases a phenomenon documented in endocrinology literature