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Epithelial restitution and barrier integrity changes would be expected to manifest as improvements in intestinal permeability assays and endoscopic healing scores, such as Simple Endoscopic Score for Crohns Disease [SES-CD] or Mayo Endoscopic Score ( Animal models have mapped specific target cell types to downstream restitution programs
This is similar to what injectable Wegovy achieves in many patients (around ~1517%)
Retrieved 2015-04-08
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