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New report calls for urgent action to avert antimicrobial resistance crisis, (2019)
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A study published in the journal Hypertension looked at the presence of trimethylamine-n-oxide (TMAO), a byproduct from digesting certain meat-based proteins in 100 adults and 22 young adults Trimethylamine N-oxide (TMAO) is derived from foods rich in choline, phosphatidylcholine, and betaine (e.g., red meat, eggs, milk, etc.) The researchers found that meat-eaters' TMAO levels rose significantly with age, as did signs of health-threatening tissue and blood vessel damage
Moreover, mitochondria-targeted antioxidant MitoTEMPO (MT) treatment not only shielded the cells from mitochondrial damage after exposure of atorvastatin as a recovery of TMRM fluorescence intensity appeared in HCM (Figures 8C,D) and in C2C12 (Figures 8E,F) but also significantly prevented atorvastatin-induced myocyte death (Supplementary Figures S5A,B)
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