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This can lead to copper sequestration in misfolded fibrils along with copper deficiency in the mitochondria, causing impaired energy production (Min et al., 2024)

The Wolverine protocol is not appropriate for patients who are pregnant or breastfeeding, have active cancer or a recent cancer history (because BPC-157 promotes angiogenesis, which could theoretically support tumor growth), or are on immunosuppressive therapy

The two peptides therefore engage non-overlapping cellular and signalling pathways that both converge on tissue repair and remodeling outcomes

Instead of targeting one pathway, combination protocols cover multiple mechanisms that operate in concert in natural tissue biology