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A large observational study or registry would be needed to fully rule it out, but given how uncommon MTC is (1 in 50k maybe) and how many have now taken GLP-1 RAs (millions), likely any major signal would have emerged by now
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Transcriptional data from these 66 treated patients were first analysed by gene set enrichment analysis (GSEA), comparing patients with good outcome (top 33% who had the best overall survival) with those with poor outcome (bottom 33% who had the poorest overall survival)
Noncompliance is a common issue with self-administered treatments
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