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The most common are gastrointestinal: Nausea the most frequently reported side effect, especially during dose increases Vomiting less common than nausea, but can occur during titration Diarrhea typically mild and temporary Constipation some patients experience this instead of or in addition to diarrhea Decreased appetite this is both a therapeutic effect and something patients notice as a side effect These side effects are generally most noticeable in the first few weeks of treatment or after a dose increase, and tend to improve as the body adjusts

[5] [8] Conform unui studiu din 2006, efectele carnitinei asupra pierderii n greutate i a echilibrului energetic au fost abordate n mai multe studii clinice

One of the first incretin agents, exenatide, was approved by the FDA in 2005, as was the first synthetic analogue of amylin, pramlintide