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The extra glucagon activation increases energy expenditure and fat oxidation, which likely accounts for the ~2% higher weight loss in trials
Semaglutide reduces hunger by slowing stomach emptying and signaling fullness to the brainyet some patients report persistent cravings or difficulty with portion control
Cardiovascular markers improved alongside weight reduction, and outcomes remained durable during extended follow-up
(Documents that pyridoxine is FDA Pregnancy Category A with increased requirements in pregnancy and is commonly used to treat morning sickness
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