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AsghariHanjani N, Vafa M
Six doses were used 0 mg (placebo), 1mg, 5 mg, 10 mg, 20 mg and 30 mg
Combination Weight Loss (CagriSema) Extensive Research The Phase 3 REDEFINE 1 trial demonstrated that CagriSema (cagrilintide 2.4 mg plus semaglutide 2.4 mg) produced mean weight loss of 20.4% at 68 weeks in 3,417 adults with obesity or overweight without diabetes, compared to 14.9% with semaglutide alone, 11.5% with cagrilintide alone, and 3.0% with placebo
The specific transition protocol accounts for receptor adaptation from prior dual agonist use
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