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SURMOUNT-1 published in the New England Journal of Medicine in July 2022, showing 22.5% weight loss at 72 weeks (Jastreboff et al., NEJM 2022)
However, data obtained from most experiments dealing with in vitro cell exposure to homocysteine are disappointing because the concentrations required are generally high and the effects generally have not been specific to homocysteine (Jacobsen, 1993)
Falcon, L
or did a dose increase
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