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People using GLP-1 drugs report seeing cosmetic changes to their faces, such as: Hollowed, sunken look, especially around the cheeks and eyes More visible lines and wrinkles Sagging, loose skin Thinning lips Other side effects of weight loss drugs In addition to the cosmetic effects of weight loss drugs, these medications can also cause health side effects
GLP-1 may induce sodium excretion by blocking sodium reabsorption in the proximal tubule through inhibition of sodium-hydrogen exchanger isoform 3 (NHE3) activity [23], as no GLP-1 receptors appear to be present in human kidneys outside of the renal vasculature [19]
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10.1523/JNEUROSCI.5749-09.2010 80 RinamanL
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