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In a study of 156 severely obese patients who underwent laparoscopic Roux-en-Y gastric bypass (LRYGB), inflammatory mediators such as serum interleukins and C-reactive protein (CRP), as well as leptin, were reduced at 6 months post-surgery
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The article is explicit that patients do not all advance on the same timeline, and some remain therapeutically effective at a mid-range amount rather than pursuing the maximum tolerated one
Bile-acid sequestrants are used to sequester bile acids in the intestine, leading to increased bile acid synthesis and consequently to a reduction in low-density lipoprotein cholesterol
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