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The Hospira label calls it "a multiple-dose container from which repeated withdrawals may be made" and instructs users to "use aseptic technique for single or multiple entry." There is no limit on the number of withdrawals
The fix: never substitute
Green CD, Maceyka M, Cowart LA, Spiegel S
Several mechanisms have been reported as responsible for cisplatin resistance, such as reduced drug uptake by a decrease in CTR1 expression, increased efflux by ABC transporters, augmented induction of stress response chaperones, induction of autophagy, inactivation of apoptosis pathway signaling, inactivation by thiol-containing proteins, and functional changes in DNA repair pathways 6,7,8,9,10,11
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