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The resulting construct, NAPstar4.3, was purified as a recombinant protein for in vitro characterisation (Fig
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Excess B12 from oral supplements is poorly absorbed at high doses (the body absorbs roughly 1 to 2% of a 1,000 mcg oral dose) and the remainder is excreted in urine
Research published in rodent models does not directly translate to canine dosing without species-adjusted calculation, body weight scaling, and route-of-administration considerations
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