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Common weekly titration schedule A common once-daily schedule starts at 0.6 mg for the first week, then moves to 1.2 mg, 1.8 mg, 2.4 mg, and 3 mg in weekly steps

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While moderate ROS levels are involved in a spectrum of signaling pathways that are vital for cell growth, differentiation, and progression, elevated ROS levels are potent triggers of cell death [7]