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According to the Joi + Blokes website, some patients report noticing changes within the first few weeks, though timelines vary and are not guaranteed

The trial was overseen and sponsored by Novo Nordisk

Such research would not only pave the way for the development of effective preventative strategies, potentially identifying individuals at higher risk and informing safer approaches to glycemic management, but also for the discovery of targeted treatment modalities that could accelerate recovery and reduce the long-term burden of this debilitating complication, particularly considering our patient did not improve with supportive care

Patients with suspected hypercortisolism require appropriate endocrine evaluation according to Endocrine Society guidelines, typically including at least two abnormal screening tests (24-hour urinary free cortisol, late-night salivary cortisol, or low-dose dexamethasone suppression testing) before confirmatory testing and specialist referral