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Ascorbic Acid (Vitamin C) An aqueous-phase antioxidant, ascorbate, plays a major role in protecting against oxidative stress, especially in a lens where its concentration (1 mM) [126] is 3035 times that of the plasma [127]

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Then, islets were handpicked and cultured at 37 C and 5% CO 2 in RPMI 1640 media (Thermo Fisher Scientific, #11875093) containing 11 mM glucose and supplemented with 5 g/l BSA fraction V (Roche, #107351080001), 100 units/ml penicillin and 100 g/ml streptomycin (1% P/S) (Thermo Fisher Scientific)