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Both are significant numbers, but tirzepatide clearly performed better.3 Another study saw a significant difference in blood sugar levels between semaglutide and tirzepatide groups, and a similar study saw improved pancreatic islet function and insulin production from its tirzepatide group compared to semaglutide.2 5 Both medications are effective for weight loss and blood sugar control, but tirzepatide appears to be the slightly more effective choice
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Silverstein said he decided to investigate the over-prescribing of B12 shots, because "as an internal medicine resident, I have seen many patients come into the emergency department, and they were getting B12 injections without having a really good reason for it." His study could not determine why family physicians were prescribing it inappropriately including whether it was initiated by the doctor or at the request of the patient
SURPASS-2 directly compared tirzepatide 15 mg to semaglutide 1 mg over 40 weeks
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