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Conversely, in some tumor contextssuch as prostate cancer or certain subsets of breast cancerFAO may be maintained or even upregulated to provide ATP and NADPH under metabolic stress, suggesting that lipid metabolism is highly plastic and tumor-type specific

While our data demonstrated clear efficacy for both compounds in reducing alcohol interoceptive effects across the tested dose ranges, it will be important in future work to assess efficacy following repeated treatment and to directly compare potential advantages in terms of efficacy, side-effect profiles, and tolerability

Lastly, by enhancing insulin sensitivity, they help in better glucose management, which can be crucial for weight loss

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