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How to Not Gain Weight After Stopping Ozempic & Other GLP-1s Key Takeaways Weight regain is common after stopping Ozempic and other GLP-1 medications because appetite rises, fullness decreases, and the routine of treatment ends

Caution is warranted when: Weight is stable but distress is high Fatigue, hormonal symptoms, or GI issues are the main concern Under-eating or nutrient deficiency is already present Muscle and bone mass are low, or frailty risk is high There is sarcopenia risk, especially in older adults BMI is in the normal range and use would be off-label without a clear medical rationale In these cases, building nutrition adequacy and strength first may improve symptoms and long-term health more than appetite suppression

If so, fluctuating hormones likely are to blame

Its nearly two-year shortage ended in October, at which time the trade group Outsourcing Facilities Association sued the FDA