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Studies show that up to 40% of people with anxiety disorders have reduced levels of B12

4 The GLP1R weight loss finding replicated in the All of Us cohort but did not replicate in UK Biobank

A greater loss of creatine from the body occurs in response to enhanced muscular activity (Kreider et al

Obese people in general are more prone to suicidal ideation, making it difficult to attribute any suicidal ideation to drugs unless a study using a direct comparison between obese patients on and off GLP1R agonists is completed.[66][67] Conclusion GLP-1 Drugs work for their intended purpose and will likely represent a revolution in the way obesity is treated as well as obesity rates in the developed world