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Typical Dosage and Guidelines Dosing Qsymia: Dosage starts at 3.75 mg/23 mg and is increased over time if needed Extended-release capsules taken by mouth once a day in the morning Take the medicine with or without food Topamax: Dosage for seizure management is 64 mg to 400 mg per day Dosage for weight loss starts at 25 mg to 50 mg once daily, not to exceed 200 mg daily While higher doses may result in more weight loss, they are also associated with more side effects

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