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Week 1-4: 1mg weekly Week 5-8: 2mg weekly Week 9-12: 4mg weekly Week 13-16: 6mg weekly Week 17-20: 8mg weekly Week 21+: 12mg weekly (if tolerated) The Phase 3 TRIUMPH-4 trial used a slightly modified approach
GLP-1 receptor agonists have been shown in rodent studies to stimulate C-cell growth in the thyroid, which raised initial concerns about thyroid cancer risk
Correct storage from reconstitution day one is the primary defense against degradation, not visual inspection alone
This led researchers to investigate liraglutide as a stand-alone treatment for obesity
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