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The mice were housed at a constant temperature and humidity under a 12-h/12-h lightdark cycle with free access to standard food and water for at least 1 week prior to the beginning of the experimental procedures
Early research demonstrated that activating GLP-1 receptors could improve insulin secretion in patients with type 2 diabetes, establishing the biological mechanism that later medications would target
These symptoms typically improve as the body adjusts to the medication over several weeks
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