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375 The haploinsufficient OPA1 mutations not only impact mtDNA maintenance but also downregulate nuclear genes encoding mitochondrial components, implying the potential role of mito-nuclear communication in ADOA
Ismail M, Alsalahi A, Imam MU, Ooi DJ, Khazaai H, Aljaberi MA, et al
I knew LDN couldnt get the job done by itself but wondered why it wasnt being added to traditional regimens
Interestingly, the regulation of this pathway appears to be context-dependent
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