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In cardiac cells, the physical proximity between mitochondria and the sarcoplasmic reticulum (SR, a specific type of ER in heart and skeletal muscle cells) allows the exchange of Ca 2+ in local microdomains, providing rapid Ca 2+ buffering

NAD + levels were measured in another clinical trial investigating the difference between different groups of the elderly, based on their amount of exercise activity, and a younger cohort 331

The full compound name and LY3437943 provide more precise identification

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