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10.3892/ijo.2024.5658 146 ZhangL.SunW.GaoW.ZhangY.ZhangP.LiuY.et al (2024)
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"Centenarians display plasma MOTS-c concentrations significantly higher than age-matched peers, a pattern that closely resembles levels found in individuals decades younger suggesting preserved mitochondrial signaling as a hallmark of exceptional longevity." The connection to cellular senescence deserves further attention here
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