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10.1016/j.freeradbiomed.2021.06.005 28 CulletonB
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[57] It suppresses appetite through a dual mechanism: it directly stimulates anorexigenic (satiety-inducing) neurons that express proopiomelanocortin (POMC) and cocaine-and amphetamine-regulated transcript (CART), while simultaneously inhibiting orexigenic (appetite-inducing) neurons that express AgRP and NPY
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