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Pieber TR, Bode B, Mertens A et al (2019) Efficacy and safety of oral semaglutide with flexible dose adjustment versus sitagliptin in type 2 diabetes (PIONEER 7): a multicentre, open-label, randomised, phase 3a trial
Its long history of safe and effective use makes it the preferred starting point for most patients
However, resistance frequently emerges through suppression of ACSL4 expression, often mediated by the ETS1/miR-23a-3p axis
[12] Short-Term Sympathomimetic Agents Phentermine, diethylpropion, phendimetrazine, and benzphetamine are sympathomimetic anorectics approved only for short-term use
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