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We treat diabetes and metabolic dysfunction with chronic daily medication (Metformin, Insulin, GLP-1s)

Combined GLP-1, oxyntomodulin and peptide YY improves body weight and glycaemia in obesity and prediabetes/type 2 diabetes: a randomized single-blinded placebo-controlled study

For women with PCOS who are actively trying to conceive, GLP-1 receptor agonists may be used in the preconception period to improve metabolic health and support weight loss, but they should be discontinued before conception with an appropriate washout period based on the specific agent

However, while they may offer a short-term feeling of lightness, theres limited solid evidence that they address the underlying issues of SIBO