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Future studies should optimize treatment parameters, including formulation, dosage, timing of administration, and assessment of brain biodistribution and explore multi-target strategies combining redox modulation with interventions that directly engage synaptic plasticity, neurotrophic signaling or critical developmental windows, to achieve functional behavioral outcomes in ASD

Guo JQ, Lin H, Lin F, Champlin R, Talpaz M, Kantarjian HM, Andreeff M , Zhao S, Glassman A, Arlinghaus R

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