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The conversion of GSSG back to GSH is facilitated by glutathione reductase (GR), resulting in variations in the GSH/GSSG ratio
In fact, oxidative stress contributes to several neurological conditions, including Parkinsons and Alzheimers diseases
Its reduced IGFBP affinity makes it a preferred tool for distinguishing receptor-mediated effects from binding-protein-mediated sequestration
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