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10.1172/JCI26640
Absinta and collaborators (108) revealed that in the edge of the chronic active MS lesion, but not in the chronic inactive ones or in the core of the lesion, MIMS and AIMS correspond to a central hub of interactions that connect with other glial populations and immune (108)
Any disruption along this pathway can lead to deficiency regardless of dietary intake, which is why some patients need supplementation even when they eat B12-rich foods
If hair preservation is a primary concern and moderate weight loss is acceptable, discussing these alternatives with your prescriber is reasonable
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