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This is substantiated by two large, randomized placebo-controlled trials, the Womens Health Initiative study 11 and the Heart and Estrogen/Progestin Replacement study 12 that found a significant reduction in the incidence of diabetes in women assigned to menopausal estrogen therapy, thus providing evidence for the antidiabetic action of estrogen in women
& Morris, S
Peptides for Targeting Chondrogenic Induction and Cartilage Regeneration in Osteoarthritis, Liao H.J., Chen H.T., Chang C.H., Journal (Cartilage, September 2024, Epub ahead of print)
The cardiovascular, metabolic, and quality-of-life benefits during treatment are substantial and well-documented
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