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Similar to their mammalian homologue, these enzymes specifically degrade intracellular GSH while yielding 5-oxoproline and cysteinylglycine (Kumar et al., 2015
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In the PACE substrate architecture, X(GD_Sh2)c cleavage may have been facilitated by an arginine residue within lysozyme located 11 positions upstream of the first proline in the GD_Sh sequence
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