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69 Metabolic reprogramming One hallmark of tumors is altered energy metabolism, with the most well-known example being the Warburg effect
This creates a clinical scenario where patients may benefit from both weight reduction and cholesterol management
In one real-world study, patients on tirzepatide lost 15.3% of their body weight at 12 months, compared to 8.3% for those on semaglutide
Differences between agents like semaglutide, liraglutide, and dulaglutide are likely modest and may be overshadowed by individual patient response and degree of metabolic improvement achieved
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