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IBI3020, a CEACAM5-targeting ADC with an undisclosed dual payload, has also shown robust antitumor activity, notable bystander effect, and a manageable safety profile in preclinical tumor models, and has just entered a phase I clinical trial in patients with unresectable, locally advanced, or metastatic solid tumors (NCT06946446) 238
Moreover, upregulation of gastric COX-1 protein and NF-B gene due to ulcer induction were abolished by both omeprazole and NPW treatments
They are intended to be used as part of a larger weight-loss plan
Ferroptosis, a new form of cell death, and its relationships with tumorous diseases
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