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In summary, DCs can initiate antitumor immunity by inducing ferroptosis in cancer cells via the TCRIFN- axis, yet their own ferroptosis, triggered by PPAR activation, PD-L1 deficiency, or XBP1-driven lipid accumulation, abrogates antigen presentation and suppresses CD8 T cell activity
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A board-certified OB/GYN and Fellow of the American College of Obstetricians and Gynecologists, she completed her Bachelor of Science in Nutrition at Cornell University, her MD at Wayne State University School of Medicine, and her residency in Obstetrics and Gynecology at Albert Einstein College of Medicine
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