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Advanced glycation end products (AGEs) exposure markedly impairs autophagic flux in renal TECs by activating the SMAD3/TFEB axis to suppress lysosome biogenesis and trigger lysosome depletion, leading to the accumulation of autophagosomes and SQSTM1/p62 (41)
Tang H, Donahoo WT, DeKosky ST, Lee YA, Kotecha P, Svensson M, et al
Adjunct Associate Professor Khoo Chin Meng, head and senior consultant at National University Hospitals division of endocrinology, said the ingredients used to make them are largely unknown
Volker Spitzer, Sarah Rickwood, and Matt Stewart discuss how structured nutrition support can bridge the gap between clinical efficacy and real-world outcomes and why collaboration across pharma, nutrition, and digital health is key to long-term success
