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(A,B) Immunostaining and cell counting results showed that co-treatment with 10 M BAY11-7082 effectively increased the number of surviving SGNs after peroxynitrite damage, while the co-treatment with 5 M or 20 M BAY11-7082 showed no significant differences in SGN number compared to the peroxynitrite-only group
The goal is consistent, effective dosing that produces predictable research outcomes
Cellular chaperones as therapeutic targets in ALS to restore protein homeostasis and improve cellular function
By day 3 a seven-fold increase in RNA and protein levels could be observed [2]
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