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Zinc oxide, specifically, has been effective in ulcer healing, performing comparably to enzymatic debriding agents for pressure ulcers [544,545,546] and demonstrating effectiveness in diabetic foot ulcers by promoting debridement through zinc oxide-medicated occlusive dressings, outperforming standard hydrocolloid dressings that utilize autodebridement [547]

Laboratory studies demonstrate that elimination of senescent cells through FOXO4-DRI administration can break the cycle of senescence induction and chronic inflammation, offering insights into interventions for age-related cellular dysfunction and tissue deterioration

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Spierer L, Tardif E, Sperdin H, Murray MM, Clarke S (2007)